Tetrahydrobiopterin Has a Glucose-Lowering Effect by Suppressing Hepatic Gluconeogenesis in an Endothelial Nitric Oxide Synthase-Dependent Manner in D... 23 Aug 2013 | 12:01 am

Endothelial nitric oxide synthase (eNOS) dysfunction induces insulin resistance and glucose intolerance. Tetrahydrobiopterin (BH4) is an essential cofactor of eNOS that regulates eNOS activity. In the...

Very Low-Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and {beta}-Cell Function in Type 2 Diabeti... 23 Aug 2013 | 12:01 am

Marked improvement in glycemic control occurs in patients with type 2 diabetes mellitus shortly after Roux-en-Y gastric bypass surgery (RYGB) and before there is major weight loss. The objective of th...

The Diabetic Brain During Hypoglycemia: In the Midst of Plenty of Lactate 23 Aug 2013 | 12:01 am

Unraveling the Mechanisms Underlying Olanzapine-Induced Insulin Resistance 23 Aug 2013 | 12:01 am

Pharmacogenetic Perturbations in Humans as a Tool to Generate Mechanistic Insight 23 Aug 2013 | 12:01 am

Does Caloric Restriction Alone Explain the Effects of Roux-en-Y Gastric Bypass on Glucose Metabolism? Not by a Long Limb 23 Aug 2013 | 12:01 am

Does Losartan Prevent Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes? 23 Aug 2013 | 12:01 am

Nutrient-Sensing Mechanisms in the Gut as Therapeutic Targets for Diabetes 23 Aug 2013 | 12:01 am

The small intestine is traditionally viewed as an organ that mediates nutrient digestion and absorption. This view has recently been revised owing to the ability of the duodenum to sense nutrient infl...

Restricted Adipogenesis in Hypertrophic Obesity: The Role of WISP2, WNT, and BMP4 23 Aug 2013 | 12:01 am

In This Issue of Diabetes 23 Aug 2013 | 12:01 am