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Hybrid T-Helper Cells: Stabilizing the Moderate Center in a Polarized System 21 Aug 2013 | 02:00 am

by Sui Huang Polarization of cell phenotypes, a common strategy to achieve cell type diversity in metazoa, results from binary cell-fate decisions in the branching pedigree of development. Such “eith...

Stable T-bet+GATA-3+ Th1/Th2 Hybrid Cells Arise In Vivo, Can Develop Directly from Naive Precursors, and Limit Immunopathologic Inflammation 21 Aug 2013 | 02:00 am

by Michael Peine, Sebastian Rausch, Caroline Helmstetter, Anja Fröhlich, Ahmed N. Hegazy, Anja A. Kühl, Christoph G. Grevelding, Thomas Höfer, Susanne Hartmann, Max Löhning Differentiated T helper (T...

Mom Knows Best: The Universality of Maternal Microbial Transmission 21 Aug 2013 | 02:00 am

by Lisa J. Funkhouser, Seth R. Bordenstein

The HILDA Complex Coordinates a Conditional Switch in the 3′-Untranslated Region of the VEGFA mRNA 21 Aug 2013 | 02:00 am

by Peng Yao, Alka A. Potdar, Partho Sarothi Ray, Sandeepa M. Eswarappa, Andrew C. Flagg, Belinda Willard, Paul L. Fox Cell regulatory circuits integrate diverse, and sometimes conflicting, environmen...

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glyc... 21 Aug 2013 | 02:00 am

by Nathan P. McNulty, Meng Wu, Alison R. Erickson, Chongle Pan, Brian K. Erickson, Eric C. Martens, Nicholas A. Pudlo, Brian D. Muegge, Bernard Henrissat, Robert L. Hettich, Jeffrey I. Gordon The hum...

The Passion Principle 14 Aug 2013 | 02:00 am

by Daniel Simberloff

Reduced Juvenile Long-Term Depression in Tuberous Sclerosis Complex Is Mitigated in Adults by Compensatory Recruitment of mGluR5 and Erk Signaling 14 Aug 2013 | 02:00 am

by Wyatt B. Potter, Trina Basu, Kenneth J. O'Riordan, Allison Kirchner, Paul Rutecki, Corinna Burger, Avtar Roopra Tuberous sclerosis complex (TSC) is a multisystem genetic disease that manifests wit...

Developmental Changes in the in Vitro Activated Regenerative Activity of Primitive Mammary Epithelial Cells 14 Aug 2013 | 02:00 am

by Maisam Makarem, Nagarajan Kannan, Long V. Nguyen, David J. H. F. Knapp, Sneha Balani, Michael D. Prater, John Stingl, Afshin Raouf, Oksana Nemirovsky, Peter Eirew, Connie J. Eaves Many normal adul...

Myelination Borrows a Trick from Phage 14 Aug 2013 | 02:00 am

by Roland G. Roberts

A Bacteriophage Tailspike Domain Promotes Self-Cleavage of a Human Membrane-Bound Transcription Factor, the Myelin Regulatory Factor MYRF 14 Aug 2013 | 02:00 am

by Zhihua Li, Yungki Park, Edward M. Marcotte Myelination of the central nervous system (CNS) is critical to vertebrate nervous systems for efficient neural signaling. CNS myelination occurs as oligo...

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