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Count-based differential expression analysis of RNA sequencing data using R and Bioconductor 27 Aug 2013 | 04:49 pm
RNA sequencing (RNA-seq) has been rapidly adopted for the profiling of transcriptomes in many areas of biology, including studies into gene regulation, development and disease. Of particular interest ...
Featured RNA-Seq Job – SENIOR BIOINFORMATICS SPECIALIST – Tufts Technology Services 27 Aug 2013 | 04:44 pm
Tufts University Job Location: Somerville, MA Job Category: Information systems / technology Posted: August 14 Tufts Technology Services (TTS) is a university-wide service organization dedicated t...
tweeDEseq: a test for differential expression based on the Poisson-Tweedie family 26 Aug 2013 | 05:00 pm
High-throughput RNA sequencing (RNA-seq) offers unprecedented power to capture the real dynamics of gene expression. Experimental designs with extensive biological replication present a unique opportu...
Whole transcriptome RNA-Seq allelic expression in human brain 26 Aug 2013 | 04:49 pm
Measuring allelic RNA expression ratios is a powerful approach for detecting cis-acting regulatory variants, RNA editing, loss of heterozygosity in cancer, copy number variation, and allele-specific e...
Calculating Sample Size Estimates for RNA Sequencing Data 23 Aug 2013 | 06:05 pm
Given the high technical reproducibility and orders of magnitude greater resolution than microarrays, next-generation sequencing of mRNA (RNA-Seq) is quickly becoming the de facto standard for measuri...
RNA-Seq Blog – Poll Results 23 Aug 2013 | 05:48 pm
We asked – What is the optimal sequencing length (cycles) for RNA-Seq experiments? Total of 118 respondents. Thanks to all who participated in the last poll. Check out our latest poll in the right ...
Uncovering hidden genes in intergenic GWAS regions with RNA capture-sequencing 22 Aug 2013 | 04:53 pm
Michael Clark, University of Queensland On Thursday, 18 July 2013, the NHGRI’s Division of Genomic Medicine presented “Current uses of and future directions for the GWAS Catalog”, a webinar highlight...
PROmiRNA: a new approach for miRNA promoter annotation based on a semi-supervised statistical model 22 Aug 2013 | 04:44 pm
The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, researchers from the Max Planck Institute for Molecular Genetics, Germany des...
Sailfish: Alignment-free Isoform Quantification from RNA-seq Reads using Lightweight Algorithms 21 Aug 2013 | 04:50 pm
RNA-seq has rapidly become the de facto technique to measure gene expression. However, the time required for analysis has not kept up with the pace of data generation. Here researchers from Carnegie M...
RNA-Seq Europe 2013 – Final Agenda Released 21 Aug 2013 | 04:40 pm
The final program for RNA-Seq Europe is now complete. Download the brochure to check out the agenda. Whether it’s a need for more accurate data, better resolution, pressure from granting agencies, or...
