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Optimizing the fabrication processes for manufacturing a hybrid hierarchical polyurethane-cell/hydrogel construct 5 Jul 2013 | 02:50 pm
It is essential to control the overall composition and internal architecture for complex organ manufacturing. In this study, several subprocesses were optimized to produce hybrid hierarchical polyuret...
Additive manufacturing of star poly({varepsilon}-caprolactone) wet-spun scaffolds for bone tissue engineering applications 5 Jul 2013 | 02:50 pm
Three-dimensional fibrous scaffolds made of a three-arm star poly(-caprolactone) were developed by employing a novel computer-aided wet-spinning apparatus to precisely control the deposition pattern o...
Bioreducible cross-linked Pluronic micelles: pH-triggered release of doxorubicin and folate-mediated cellular uptake 5 Jul 2013 | 02:50 pm
Bioreducible are described here, cross-linked Pluronic micelles carrying doxorubicin (DOX) for folate-mediated cancer targeting. The amine-terminated Pluronic® F-127 was functionalized by grafting acr...
The synthesis and characterization of a thermally responsive hyaluronic acid/Pluronic copolymer and an evaluation of its potential as an artificial vi... 5 Jul 2013 | 02:50 pm
A smart in situ polymerizable artificial vitreous substitute was synthesized via the copolymerization of hyaluronic acid and Pluronic® F-127. This copolymer has a unique sol–gel transition at differen...
Ibuprofen-loaded chitosan/poly(maleic anhydride-alt-vinyl acetate) submicronic capsules for pain treatment 5 Jul 2013 | 02:50 pm
A new approach to prepare polymeric capsules was developed to obtain an efficient controlled release system for pain treatment. Capsules with a mean diameter between 400 and 1000 nm were prepared usin...
Hybrid biodegradable membranes of silane-treated chitosan/soy protein for biomedical applications 5 Jul 2013 | 02:50 pm
In recent years, progress in the field of hybrid materials has been accelerated through use of the sol–gel process for creating materials and devices, which benefit from the incorporation of both inor...
Silver sulfadiazine-immobilized celluloses as biocompatible polymeric biocides 5 Jul 2013 | 02:50 pm
Sulfadiazine was immobilized onto cotton cellulose using ethylene glycol diglycidyl ether as a binder. Upon treatment with diluted silver nitrate aqueous solution, the sulfadiazine moieties in the imm...
Preparation of an adipose-derived stem cell/fibrin-poly(D,L-lactic-co-glycolic acid) construct based on a rapid prototyping technique 24 May 2013 | 11:37 am
Currently, large, thick, and complex tissue vascularization is one of the research focuses of tissue engineering. Numerous studies have proven that microvascular systems can be developed by cultivatin...
The effectiveness, cytotoxicity, and intracellular trafficking of nonviral vectors for gene delivery to bone mesenchymal stem cells 24 May 2013 | 11:37 am
Nonviral gene delivery that enables exogenous gene expression in bone mesenchymal stem cells could accelerate clinical application of cell-based gene therapy. This study systematically investigated an...
Nuclear location signal peptide-modified poly (ethyleneimine)/DNA complexes: An efficient gene delivery vector in vitro and in vivo 24 May 2013 | 11:37 am
The low transfection efficiency of nonviral gene delivery systems limits their applications. In this study, we demonstrated a simple method to modify poly(ethyleneimine)/DNA complexes with a nuclear l...
