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Case studies from the list of human regions not in Pfam 27.0. 14 May 2013 | 01:21 pm

Following on from Jaina and Marco’s blog post last week about conserved Human regions not in Pfam, I would like to give you some examples of how we have used the regions identified to improve existing...

Pfam targets conserved human regions 7 May 2013 | 03:20 pm

Recently, we have been looking at how much of the human proteome is covered by Pfam (release 27.0), and ways in which we can improve this coverage. We have even written an open access paper about it t...

TreeFam 9 is now available! 3 May 2013 | 01:10 pm

We are happy to announce that TreeFam 9 is online and you can find it under http://www.treefam.org. TreeFam 9 now has 109 species (vs. 79 in TreeFam 8) and is based on data from Ensembl v69, Ensembl G...

Pfam 27.0 is now available! 22 Mar 2013 | 10:42 pm

In a blog post published just over a year ago, I proposed a number of changes to the content of Pfam to improve scalability and usability of the database.  These changes came into effect a few days ag...

Dfam 1.1 released 15 Nov 2012 | 07:13 pm

We are pleased to announce that we’ve released Dfam 1.1. This version represents a few important changes from 1.0, including updated hit results, a new tab for each entry page showing relationships to...

What’s new in AntiFam? 13 Nov 2012 | 02:31 pm

We have recently produced a new release of AntiFam, release 3.0. AntiFam has grown in size, and release 3.0 contains 54 entries – compared to just 23 when we last blogged about AntiFam (release 1.1). ...

We’re on the move 1 Nov 2012 | 02:48 pm

After 15 great years at the Sanger Institute we are on the move. On the 1st November, the Cambridge Xfam group will be taking up residence at the European Bioinformatics Institute on the other side of...

Dfam: A database of repetitive DNA elements 6 Sep 2012 | 06:28 pm

We are pleased to introduce Dfam 1.0, a database of profile HMMs for repetitive DNA elements. Repetitive DNA, especially the remnants of transposable elements, makes up a large fraction of many genome...

Getting all Pfam-A domains for a proteome 21 Jun 2012 | 09:49 pm

We’ve had a few helpdesk tickets in the last few months asking how to download all of the Pfam-A domains for a particular species. This information can be quite difficult to obtain: getting it require...

Does my family of interest have a determined 3D protein structure? 10 May 2012 | 02:55 am

Two related questions that we are often asked via the Pfam helpdesk is ‘Which families have a known three-dimensional structure?’ and ‘Why is a particular a PDB structure not found in Pfam’.  You may ...

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