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Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling 1 Nov 2011 | 09:23 pm
”Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling” Cell. 147: 565-76. TGF-β signalling directs various responses through the transcription factor Smad2/3. The c...
FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis 31 Oct 2011 | 10:11 pm
”FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis” Cancer Cell. 20: 427-42. In this paper, using a Flag-tag affinity procedure coupled w...
Reprogramming Transcription By Distinct Classes of Enhancers Functionally Defined By eRNA 29 May 2011 | 04:38 am
”Reprogramming Transcription By Distinct Classes of Enhancers Functionally Defined By eRNA” Nature. 474: 390–394. In this paper, the authors found out a ‘hidden’ transcription programme in prostate ...
Mapping And Analysis of Chromatin State Dynamics In Nine Human Cell Types 23 May 2011 | 06:19 pm
”Mapping And Analysis of Chromatin State Dynamics In Nine Human Cell Types” Nature. 473: 43-9. Transcipts: Slide 2: As we know, chromatin is the state in which DNA is packaged in a living cell and...
Histone H3K27ac Separates Active From Poised Enhancers And Predicts Developmental State 4 Apr 2011 | 07:32 pm
”Histone H3K27ac Separates Active From Poised Enhancers And Predicts Developmental State” Proc Natl Acad Sci U S A. 107: 21931-6. H3K4me1 and p300 are two well-known markers for active enhancers. Ho...
Activator Control of Nucleosome Occupancy In Activation And Repression of Transcription 27 Mar 2011 | 04:44 am
”Activator Control of Nucleosome Occupancy In Activation And Repression of Transcription” PLoS Biol. 6: 2928-39. The GAL1 and GAL10 genes are separated by a 680 bp bidirectional promoter, which cont...
Epigenetics Switch Involved In Activation of Pioneer Transcription Factor FOXA1-dependent Enhancers 23 Mar 2011 | 01:21 am
”Epigenetics Switch Involved In Activation of Pioneer Transcription Factor FOXA1-dependent Enhancers” Genome Res. 21: 555-565. FOXA1 is a pioneer transcription factor which often binds to enhancers ...
A Unique Chromatin Signature Uncovers Early Developmental Enhancers In Humans 15 Feb 2011 | 12:48 am
”A Unique Chromatin Signature Uncovers Early Developmental Enhancers In Humans” Nature. 470: 279-83. Recent evidence has suggested that active enhancers usually can be identified by p300 binding. In...
Quantitative Models of The Mechanisms That Control Genome-Wide Patterns of Transcription Factor Binding During Early Drosophila Development 8 Feb 2011 | 11:35 pm
”Quantitative Models of The Mechanisms That Control Genome-Wide Patterns of Transcription Factor Binding During Early Drosophila Development” PLos Genetics. 7: e1001290 Animal transcription factors ...
Distinct Roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac In Nuclear Receptor Transactivation 23 Jan 2011 | 03:40 am
”Distinct Roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac In Nuclear Receptor Transactivation” EMBO J. 30: 249-62. In this paper, the authors used MEFs system to investigate the ...
